Title: Scientist I, TCR-T Engineering and Translation
Location: Upper East Side
Org Unit: MCC Laboratories
Work Days:
Weekly Hours: 35.00
Exemption Status: Exempt
Salary Range: $70,200.00 - $83,200.00
*As required under NYC Human Rights Law Int 1208-2018 - Salary range for this role when Hired for NYC Offices
Position Summary
Supports the development of next-generation T cell receptor (TCR)-engineered T cell therapies by preparing engineered TCR-T cells and testing their biological properties. This role reports to the Assistant Lead and works collaboratively with the broader team to deliver IND ready candidates for the clinic.
Job Responsibilities
- Support IND enabling preclinical studies for TCR-T cell programs.
- Generate engineered TCR-transduced T cells using molecular and genomic technologies/platforms.
- Perform cell-based function assays examining biological properties in vitro
- Assist in testing potency of TCR-T cells in tumor models in vivo.
- Analyze experimental data, prepare summaries, and present findings at team meetings.
- Maintain accurate and detailed record keeping of experimental methods and results in laboratory notebooks, write SOPs.
- As needed, assist in training researchers and laboratory staff in equipment use and experimental techniques.
- Operate with highest integrity and ethics, conduct all experiments following lab, department, and college policies and procedures.
- Collaborate cross-functionally with teams including TCR discovery and vector development.
- Stay current with literature and emerging technologies in the field. Contribute to writing of scientific posters and/or manuscripts.
- Perform other related duties as assigned.
Education
- Bachelor's Degree in Biology, Biochemistry or related field
Experience
- Minimum 8+ years research experience in an academic laboratory or in the biotechnology or pharmaceutical industry.
- Prior experience in manipulating and culturing human T cells, T cell engineering, molecular and cell biology techniques, conduct and analysis methods in adoptive T cell therapy using mouse tumor models.
Knowledge, Skills and Abilities
- Highly collaborative, ability to multitask and work cross-functionally.
- Strong organizational skills with the ability to pay close attention to detail.
- Excellent written and verbal communication skills.
Licenses and Certifications
Working Conditions/Physical Demands
Standard laboratory conditions; This position may require standing or sitting for long periods of time; This role may require working within Biologic Safety Level 1 and 2.
Cornell welcomes students, faculty, and staff with diverse backgrounds from across the globe to pursue world-class education and career opportunities, to further the founding principle of “any person, any study.” No person shall be denied employment on the basis of any legally protected status or subjected to prohibited discrimination involving, but not limited to, such factors as race, ethnic or national origin, citizenship and immigration status, color, sex, pregnancy or pregnancy-related conditions, age, creed, religion, arrest and/or conviction record, military or veteran status, sexual orientation, gender expression and/or identity, an individual’s genetic information, domestic violence victim status, familial status, marital status, or any other characteristic protected by applicable federal, state, or local law.
Cornell University embraces diversity in its workforce and seeks job candidates who will contribute to a climate that supports students, faculty, and staff of all identities and backgrounds. We hire based on merit, and encourage people from historically underrepresented and/or marginalized identities to apply. Consistent with federal law, Cornell engages in affirmative action in employment for qualified protected veterans as defined in the Vietnam Era Veterans’ Readjustment Assistance Act (VEVRRA). We also recognize a lawful preference in employment practices for Native Americans living on or near Indian reservations in accordance with applicable law.
